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WinGPC UniChrom software modules

Grow at your pace in any way you choose. The WinGPC UniChrom software modules fit seamlessly into any WinGPC configuration.

The following modules are available:

Report Designer

P/N 400-1012

Multi instrument control

P/N 400-0301 to 400-0306


P/N 400-1080

Compliance Pack

P/N 400-1011

Viscosity module

P/N 400-1002 (Triple detection: add P/N 400-1003)

Light Scattering modules

P/N 400-1003 (LALLS/RALLS)   P/N 400-1004 (TALLS, MALLS)

Heparin/End group module

P/N 400-1007

Copolymer module

P/N 400-1006

Chemical heterogeneity module

P/N 400-1009

2D Chromatography module

P/N 400-1008

Mass spectrometry module

P/N 400-1015

WinGPC Example Report

The Report Designer is the ultimate tool for optimum output and performance, setting desktop publishing quality standards in industry. Reports can be printed on any printer, Windows output device or published directly as PDF, JPEG, HTML or Microsoft Excel. The Report Designer excels in the fast and simple distribution of analytical information via e-mail, LIM systems, Intranet and Extranet.

All WinGPC UniChrom options and software modules are supported by the Report Designer. Results of different modes (e.g. molar mass averages, light scattering evaluation, HPLC quantification or multi area analysis) can be combined on one report, consisting of one or more pages. The customized layouts can substitute the default WinGPC UniChrom reports, also during automatic evaluation or batch printing.

The WinGPC UniChrom ReportDesigner offers options that outshine any report presentation tool. Work flow support on many levels helps to organize and manage samples, reports and resource

  • lab statistics for the WinGPC UniChrom sample databases
  • automatic calculation, e.g. of averages for repeated injections
  • automatic intelligent rounding of results
  • comment options during printout
  • appearance conditions for elements according to user selectable flags
  • powerful overlay presentation with automatic sorting for screening experiments
  • chart objects (2D, 3D) and cross tables for clearly arranged result presentation
  • software wizard and syntax check faciliate creating and editing new layouts

Part number: 400-1012
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Multi instrument control

These modules add additional time bases to WinGPC. The addition of instruments to an existing UniChrom installation is seamless and easy.

  • Plug-in the instrument(s)
  • Add the license file for more instruments
  • Benefit from running independent systems in a single environment

The new instruments gain the WinGPC UniChrom advantages already experienced, maintaining the existing configurations, data, and methods. Seamless software integration alliviates the need for re-installation, re-validation, or additional training. Already available software modules can be used in all time bases.

Part numbers:

  • from 1 instrument to 2 instruments:     400-0301
  • from 1 instrument to 3 instruments:     400-0302
  • from 1 instrument to 4 instruments:     400-0303
  • from 2 instrument to 3 instruments:     400-0304
  • from 2 instrument to 4 instruments:     400-0305
  • from 3 instrument to 4 instruments:     400-0306

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SystemPilot with instrument control. Typical GPC/SEC end actions (reduce flow, turn UV lamp off...) can be choosen to be executed after the sequence or when closing WinGPC.

The WinGPC module ChromPilot adds comprehensive and convenient system control via WinGPC UniChrom to the overall functionality. Supported systems are 

  • PSS SECcurity GPC System
  • EcoSEC semi-micro GPC System
  • HP/Agilent 1100 System
  • Agilent 1200/1260/1290 System
  • Agilent 1120/1220 System 
  • Shimadzu Nexera, Prominence, LC-8/10/20A
  • Dionex UHPLC+ Focused, UltiMate 3000
  • Shodex RI 100/200
  • Wyatt DAWN DSP, DAWN EOS, Mini-Dawn


Up to four different systems can be controlled with one WinGPC license. Scalable design allows access to fully controlled systems and partial or not controlled systems at the same time. Mixed systems are fully supported.

Status and settings of the controlled system are displayed in the Instrument Manager, providing all information at one glance. The operation and the definition of typical GPC/SEC "end actions" can be done coherently in one overview window. WinGPC specific features, like overlaid injection, can still be used. The ChromPilot adds one instrument logbook for every controlled system and shows important instrument status information.

The ChrommPilot seamlessly integrates in existing installations. Existing sample lists are fully compatible and can be used as are. The ChromPilot can be used with any WinGPC software module and is integrated into the Compliance Pack.

Part number: 400-1080
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Compliance Pack

WinGPC Unity Compliance Pack Administration tool for setting user rights and selecting user groups.

The WinGPC UniChrom Compliance Pack meets GAMP 4, GxP, ICH, and FDA 21 CFR part 11 (electronic records and electronic signature) requirements for GPC/SEC analysis.

It adds 

  • secure login with unique username and password
  • sample and session audit trails
  • an administration tool to define and select user levels
  • electronic signatures

to the general functionality.

To support IQ (installation qualification) and OQ/PV (operational qualification/performance verifaction) convenient validation and verification tools are added.

Part number: 400-1011
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Viscosity module

Mark-Houwink plot with measured specific and intrinsic viscosity and branching index g'. g' is obtained by comparison with the linear counterpart (blue).

The WinGPC Viscosity module supports all on-line viscometers regardless of manufacturer or design principle. Single, dual, and four capillary viscometers can be connected using the sophisticated PSS data acquisition hardware. WinGPC can handle pressure signals (delta pressure and inlet pressure) as well as specific viscosity signals. Any concentration detector (RI, UV, and others) can be used to determine the intrinsic viscosity. 

The viscosity module adds:

  • specific viscosity and intrinsic viscosity as bulk and slice value
  • determination of Mark-Houwink coefficients, Mark-Houwink plot
  • universal calibration option for viscometry detection
  • molecular weight averages, molecular weight distribution, cumulative distribution
  • branching index (contraction factor) g', g' averages
  • structural information

A comment on triple detection: 
The use of viscometry in conjunction with RALLS (Triple detection) has become standard methodology to overcome the limitations posed by 90° light scattering only. The combination of the WinGPC Viscometry module and one of the WinGPC light scattering modules adds automatically triple evaluation capability. 

WinGPC UniChrom goes one step further by combining MALLS with viscometry. This allows for the unambiguous absolute measurement of molar masses, branching, aggregation, agglomeration, structure parameters, and gel content.

Part number: 400-1002
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related products:

PSS viscometer eta2010

Light scattering modules

WinGPC Unity MALLS window, for LALLS or RALLS detectors only the left part of the window would be available.

The WinGPC light scattering modules support all light scattering detectors regardless of manufacturer and measuring principle. WinGPC Unity offers two light scattering modules which main difference is the number of supported angles. For applications that can be restricted to a single angle (LALLS, RALLS) the LS module is the suitable choice, others need the MALLS module that supports multi angle light scattering detectors with up to 18 angles. 

The LS module adds:

  • absolute molecular weight averages, molecular weight distribution, cumulative distribution based on light scattering data evaluation
  • dn/dc determination or mass recovery determination
  • comparison with conventional calibration results
  • in combination with the viscometry module: triple detection and comparison with universal calibration and triple detection results

The MALLS module additionally adds:

  • Rg, molecular size
  • evaluation options: Zimm, Debye, Berry
  • branching information g, g averages
  • structural information

Part numbers:

  • LS module:                                            400-1003
  • MALLS module:                                       400-1004
  • Upgrade from LS to MALLS module:           400-1005

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related products:

PSS light scattering detector SLD7000

PSS dn/dc instruments

Heparin/End group analysis module

WinGPC Elugram window with RI and UV detector signal and overlaid calibration curve.

The end group analysis module allows to determine functionality distribution and even molecular weight without the need for calibration standards or light scattering detection.

The end group analysis module requires two independent concentration detector signals (e.g. RI and UV) for the automatic calculation of the results.

Additionally this module supports the analysis of heparin products in full compliance with national and international pharmacopoeias (e.g. EP, USP, JP, DAB). From the calibration standard CRS a calibration curve is automatically constructed. This calibration curve is used to measure the absolute molar masses of low molecular weight heparins as well as the mass percentage lower than 8 000 Da. 

Other heparin analysis methods (e.g. using broad standards for calibration) are already part of WinGPC Unity and do not require this module.

Part number: 400-1007

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Copolymer module

Copolymers have a chemical composition distribution (CCD) and a molar mass distribution (MMD) and are therefore complex polymers. The copolymer module allows comonomer distribution analysis with WinGPC Unity.

It adds

  • average chemical composition analysis
  • comonomer distribution
  • copolymer molecular weight averages and distribution

This method needs two independent concentration detector signals for the automatic calculation of the composition and is based on the multiple detection approach of copolymer calibration. This method requires molar mass calibration and an additional detector response calibration. Other kind of information, parameters or special equipment is not necessary.

Part number: 400-1006
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Chemical heterogeneity module

WinGPC Unity Chemical Heterogeneity Result window

The chemical heterogeneity module allows the analysis of chemically heterogeneous polymers (e.g. copolymers, endgroup functionalized polymers) in the interaction mode of chromatography (HPLC). This method requires a calibration of (HPLC) retention with standards of known chemical composition. The chemical heterogeneity module is an alternative for the copolymer module which calculates composition based on the detector response.

The module adds

  • the average chemical composition G,
  • the skew, S, and the width, dG, of the compositional distribution

Part number: 400-1009
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2D Chromatography module

WinGPC Unity 2D module combining HPLC and GPC/SEC.

The 2D Chromatography module combines the separation power of two different chromatographic methods (dimensions). This results in a dramatical enhancement of resolution and peak capacity as well as in-depth information on complex products. All kinds of detectors can be used in both dimensions. 

The 2D Chromatography module is the module of choice for copolymers with a large number of hetero-contacts, e.g. statistical copolymers, polymers with only short comonomer sequences and high side chain densities. 

WinGPC with 2D chromatography supports any separation technique for the first and the second dimension: 

  • HPLC
  • TREF
  • IC
  • CE
  • GC
  • and others.

An automated transfer valve, controlled by WinGPC and operated with a convient software wizard, transfers sample slices from the first into the second dimension. The 2D chromatography module creates 3D surface plots and contour maps from the data. Evaluation, e.g. determination of molar mass or chemical distribution, is achieved by calibration of both axes. 

The WinGPC modules Copolymer and Chemical Heterogeneity are useful additions to the 2D module, to have all calibration options available.

For more information on Polymer-HPLC coupled with GPC/SEC download our primer

Part number: 400-1008
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Mass spectrometry module

The mass spectrometry module supports MZXML data import of mass spectrometry data to WinGPC UniChrom. The mass spectrum for every elution volume slice can be reviewed with automatic assignement of degree of charge, the degree of polymerization and the molar mass of the end group. A dedicated calibration curve can be created after automatic band broadening correction to receive true molar masses.

Part number: 400-1015
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